The widely used anesthetic agent propofol can replace α-tocopherol as an antioxidant

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assessment of propofol usefulness as an anesthetic agent during colonoscopy

â  background propofol is used as a sedative drug during colonoscopy. in this study we analyzed the adverse effects of propofol (i.e., hemodyâ­namic and respiratory) on patients who underwent colonoscopies. me t hod s this study was performed in qom province, iran. in this study, 125 patients (63 females, 62 males) were enrolled. study patients were administered (0.5-1.5 mg/kg) intravenous prop...

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Assessment of Propofol Usefulness as an Anesthetic Agent During Colonoscopy

BACKGROUND Propofol is used as a sedative drug during colonoscopy. In this study we analyzed the adverse effects of propofol (i.e., hemodynamic and respiratory) on patients who underwent colonoscopies. METHODS This study was performed in Qom Province, Iran. In this study, 125 patients (63 females, 62 males) were enrolled. Study patients were administered (0.5-1.5 mg/kg) intravenous propofol by ...

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Urinary α-carboxyethyl hydroxychroman can be used as a predictor of α-tocopherol adequacy, as demonstrated in the Energetics Study.

BACKGROUND Other than the in vitro erythrocyte hemolysis test, no valid biomarkers of vitamin E status currently exist. OBJECTIVE We hypothesized that the urinary vitamin E metabolite α-carboxyethyl hydroxychroman (α-CEHC) could serve as a biomarker. DESIGN The relations between urinary α-CEHC, plasma α-tocopherol, and vitamin E intakes were assessed by using a previously validated multipas...

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How does the anesthetic agent propofol affect tumors?

Propofol is one of the most popular intravenous agents used for induction and maintenance of anesthesia. Numerous studies have intended to explore whether or how propofol affects tumor metastasis and invasion but the results are conflicting. Propofol can influence cancer progression through indirectly affecting the function of immune cells such as T cells, NK cells or macrophages and directly i...

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Propofol: an anesthetic possessing neuroprotective effects.

Propofol is a short-acting intravenous anaesthetic agent and widely used not only in operating rooms but also in the intensive care unit (ICU). Apart from its multiple anaesthetic advantages, the neuroprotective effect of propofol has been demonstrated in diverse models of neuronal injury. The effect of propofol results from activation of gamma-aminobutyric acid (GABA) receptor, modulation exci...

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 1995

ISSN: 0014-5793

DOI: 10.1016/0014-5793(94)01337-z